Clinical studies

MANA is based on the scientific statements of EFSA and WHO and further on more than 44 clinical studies related to our ingredients. On their basis, we are allowed to state health claims.

MANA Powder and MANA Drink are based on more than 44 clinical studies related to our ingredients and contained vitamins, minerals and other nutrients. These studies were the basis for the scientific committee of EFSA (European Food Safety Authority), which assessed the accuracy of the proposed health claims of various nutrients for the legislative purpose.

Raw materials used in MANA Powder and MANA Drink and their content of vitamins, minerals and nutrients allow us to put health claims. These claims were approved by the scientific committee of EFSA and are listed below. MANA Powder and MANA Drink and also based on other scientific opinions from EFSA and WHO (World Health Organization). These scientific opinions are always based on current clinical and other studies and they are reflecting the current state of knowledge.

 

We are the first and only manufacturer of powdered diet that is able to declare such claims.

 

The following is a list of ingredients, vitamins, minerals and nutrients, where we place health claims. We also point out the benefits of a healthy lifestyle and we provide a link to a particular clinical study, on which the scientific committee based its decision.


Beta-glucans

Consummation of 3 g of beta-glucans per day contributes to the maintenance of normal blood cholesterol levels. MANA is rich in beta-glucans. The MANA Drink has 6.60 grams and MANA Powder has 9.46 grams of beta-glucan per daily dose.

Enjoy MANA as part of a varied and balanced diet and a healthy lifestyle. MANA is suitable for every healthy adult.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2011.2470/epdf

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2011.2207/epdf


Proteins, isolated protein from soy

This highly valuable protein contributes to muscle growth, its maintenance and to maintaining normal bones. Thanks to the overall protein content of 20 g per serving, MANA Powder and MANA Drink are also ranked among foods with high protein content.

Enjoy MANA as part of a varied and balanced diet and a healthy lifestyle. MANA is suitable for every healthy adult.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1811/epdf 


Vitamin B7, Biotin

It has been shown that the daily consumption of 22.5 mcg of biotin contributes to normal energy-yielding metabolism, to normal functioning of the nervous system, to normal macronutrient metabolism and to normal psychological function. Biotin further contributes to the maintenance of normal hair, normal mucous membranes and normal skin. With daily consumption of 5 servings of MANA Powder or MANA Drink, your daily intake will be 50 mcg of biotin.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1209/epdf


Potassium

Potassium contributes to normal functioning of the nervous system, to normal muscle function and to the maintenance of normal blood pressure. By consumption of 5 servings of MANA Powder or MANA Drink a day, your daily intake of potassium will be 2 grams.

Enjoy MANA as part of a varied and balanced diet and a healthy lifestyle. MANA is suitable for every healthy adult.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1469/epdf


Folate, folic acid, vitamin B9

In the human body, folate contributes to normal amino acid synthesis, to normal blood formation, to normal homocysteine metabolism, to normal psychological function and to the normal function of the immune system. Folate further contributes to the reduction of tiredness and fatigue and has a role in the process of cell division. It also contributes to maternal tissue growth during pregnancy.

By daily consumption of 5 servings of MANA Powder or MANA Drink, your daily intake of folic acid will be 220 mcg.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1760/epdf


Phosphorus

Phosphorus contributes to energy-yielding metabolism, to normal function of cell membranes, maintenance of normal condition of bones and teeth. When you eat 5 servings MANA Powder or MANA Drink, your daily intake of phosphorus will be 1.5 grams.

Enjoy MANA as part of a varied and balanced diet and a healthy lifestyle. MANA is suitable for every healthy adult.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1219/epdf


Magnesium

An adequate intake of Magnesium contributes to a reduction of tiredness and fatigue, to electrolyte balance, to normal energy-yielding metabolism,  to normal functioning of the nervous system, to normal muscle function and to normal protein synthesis. Magnesium further contributes to normal psychological function, to the maintenance of normal bones and teeth and has a role in the process of cell division. By daily consumption of 5 servings MANA Powder or MANA Drink, your daily intake of magnesium will be 375 mg.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2013.3331/epdf

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1216/epdf


Chlorine / chlorides

It has been shown that the consumption of chloride contributes to normal digestion by production of hydrochloric acid in the stomach. 5 servings of MANA Powder will deliver 1.9 grams of chloride, consumption of 5 servings of MANA Drink delivers 2.1 grams of chloride.

Enjoy MANA and MANA Drink as part of a varied and balanced diet and a healthy lifestyle. MANA is suitable for every healthy adult.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1764/epdf


Chromium

It has been shown that chromium contributes to normal macronutrient metabolism and to the maintenance of normal blood glucose levels. By daily consumption of 5 servings of MANA Powder, the chromium intake will be 67 mcg. By daily consumption of 5 servings of MANA Drink, the chromium intake will be 60 mcg.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1732/epdf


Iodine

It has been proved that iodine contributes to normal cognitive function, to normal energy-yielding metabolism, to normal functioning of the nervous system, to the maintenance of normal skin and to the normal production of thyroid hormones and normal thyroid function. The recommended daily intake for a healthy adult is according WHO 150 mcg. By consuming 5 servings of MANA Powder or MANA Drink a day, your intake of iodine is 150 mcg.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2014.3516/epdf

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2014.3517/epdf


Lipids from sea algae, DHA and EPA

Algal lipids contain the unsaturated fatty acids DHA and EPA, witch contribute to the normal function of the heart. DHA also contributes to maintenance of normal brain function and normal vision with daily intake of 250 mg. 5 servings of MANA Powder or MANA Drink supply 1237 mg of these acids, of which 825 mg of DHA. For food supplements and/or fortified foods is important not to exceed a supplemental daily intake of 5 g of EPA and DHA combined.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1263/epdf


Pantothenic acid, vitamin B5

It has been shown that pantothenic acid contributes to normal energy-yielding metabolism, to normal synthesis and metabolism of steroid hormones, vitamin D and certain neurotransmitters. Pantothenic acid further contributes to the reduction of tiredness and fatigue and contributes to normal mental performance.

By daily consumption of 5 servings of MANA Powder or MANA Drink, the intake  of pantothenic acid will be 6 mg.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2013.3411/epdf


Manganese

It was shown manganese contributes to normal energy-yielding metabolism, to the maintenance of normal bones, to the normal formation of connective tissue and to the protection of cells from oxidative stress. 5 servings of MANA Powder contains 3,5 mg of manganese, and 5 servings of MANA Drink 2 mg.

Enjoy MANA and MANA Drink as part of a varied and balanced diet and a healthy lifestyle. MANA is suitable for every healthy adult.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1808/epdf

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1217/epdf


Copper

It has been shown that the copper contributes to main­tenance of normal connective tissues, to normal energy-yielding metabolism, to normal functioning of the nervous system and to normal hair and skin pigmentation. Further, it contributes to normal iron transport in the body, to the normal function of the immune system and to the protection of cells from oxidative stress. By daily consumption of 5 servings MANA Powder or MANA Drink, your daily intake of copper will be 1.5 mg.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1211/epdf


Molybdenum

It has been proven that molybdenum contributes to the normal metabolism of sulfur amino acids. 5 servings of MANA or MANA Drink has 200 mcg of molybdenum.

Enjoy MANA Powder and MANA Drink as part of a varied and balanced diet and a healthy lifestyle. MANA is suitable for every healthy adult.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1745/epdf


Lipids from canola, alpha-linolenic acid

Canola oil is a superior source of linoleum acid. This acid contributes to the maintenance of normal blood cholesterol levels.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1252/epdf


Vitamin B3, niacin

Niacin contributes to normal energy-yielding metabolism, to normal functioning of the nervous system, to normal psychological function, to the maintenance of normal mucous membranes, to the maintenance of normal skin and to the reduction of tiredness and fatigue. By daily consumption of 5 servings of MANA Powder or MANA Drink, the  intake of niacin is 16 mg.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1224/epdf


Vitamin B2, riboflavin

Riboflavin contributes to normal energy-yielding metabolism, to the normal functioning of the nervous system, to the maintenance of normal mucous membranes, skin, vision and red blood cells. Further, it contributes to the normal metabolism of iron, to the protection of cells from oxidative stress and the reduction of tiredness and fatigue. By daily consumption of 5 servings of MANA Powder or MANA Drink, the daily income of riboflavin will be 1.5 mg.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1814/epdf


Selenium 

There is evidence that selenium contributes to normal spermatogenesis, to the maintenance of normal hair and nails. Further, it contributes to normal function of the immune system, to the normal thyroid function and to the protection of cells from oxidative stress. By daily consumption of 5 servings MANA Powder or MANA Drink, the intake of selenium will be 55 mcg.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1727/epdf


Vitamin B1, thiamine

Thiamin contributes to normal energy-yielding metabolism, to normal functioning of the nervous system, to normal psychological function and to the normal function of the heart. By daily consumption of 5 servings MANA Powder or MANA Drink, the daily intake of thiamine is 1.1 mg.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1755/epdf


Calcium

IIt is proved that calcium contributes to normal blood clotting, to normal energy-yielding metabolism, to normal muscle function, to normal neurotransmission and to the normal function of digestive enzymes. Further, calcium has a role in the process of cell division and specialisation. It is also needed for the maintenance of normal bones and teeth. By daily consumption of 5 servings MANA Powder or MANA Drink , your calcium intake will be 800 mg.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1272/epdf

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1210/epdf


Vitamin A, retinol

Vitamin A contributes to normal iron metabolism, to the maintenance of normal mucous membranes, skin and vision. Vitamin A also contributes to the normal function of the immune system and has a role in the process of cell specialisation. 5 servings of MANA Powder or MANA Drink contains 800 mcg of vitamin A (retinol).

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1221/epdf


Vitamin B12, cobalamin

Vitamin B12 contributes to normal energy-yielding metabolism, to normal functioning of the nervous system, to normal homocysteine metabolism, to normal psychological function and to normal red blood cell formation. Further, it contributes to the normal function of the immune system and to the reduction of tiredness and fatigue. Vitamin B12 has also a role in the process of cell division. By daily consumption of 5 servings of MANA Powder or MANA Drink, the intake of vitamin B12 (cyanocobalamin form) is 5 mcg.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1756/epdf


Vitamin B6, pyridoxine, pyridoxol

Vitamin B6 contributes to normal cysteine synthesis, to normal energy-yielding metabolism, to normal functioning of the nervous system, to normal homocysteine metabolism and to normal protein and glycogen metabolism. Vitamin B6 further contributes to normal psychological function, to normal red blood cell formation and to the reduction of tiredness and fatigue. This vitamin also contributes to the normal function of the immune system and to the regulation of hormonal activity. By daily consumption of 5 servings of MANA Powder or MANA Drink the  intake of vitamin B6 (pyridoxin form) will be 1,5 mg.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1759/epdf


Vitamin C, ascorbic acid

Vitamin C contributes to maintain the normal function of the immune system during and after intense physical exercise. Further, it contributes to normal collagen formation for the normal function of blood vessels, bones, cartilage, gums, skin and teeth. Vitamin C also contributes to normal energy-yielding metabolism, to normal functioning of the nervous system, to normal psychological function and to the normal function of the immune system. Vitamin C further contributes to the protection of cells from oxidative stress, to the reduction of tiredness and fatigue, to the regeneration of the reduced form of vitamin E and increases iron absorption.

By daily consumption of 5 servings of MANA Powder or MANA Drink, the intake of vitamin C will be 80 mg.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1815/epdf

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1226/epdf


Vitamin D, ergocalciferol

Vitamin D contributes to normal absorption/utilisation of calcium and phosphorus, to normal blood calcium levels, to the maintenance of normal bones, to the maintenance of normal muscle function and to the maintenance of normal teeth. Vitamin D also contributes to the normal function of the immune system and has a role in the process of cell division. By daily consumption of 5 servings of MANA Powder or MANA Drink, the daily intake of vitamin D (ergocalciferol) is 6,5 mcg.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2014.3579/epdf


Vitamin E, alfa-tocopherol

Vitamin E contributes to the protection of cells from oxidative stress. By daily consumption of 5 servings MANA Powder or MANA Drink, the daily intake of vitamin E (alpha-tocopherol) will be 12,5 mg.

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1816/epdf


Vitamin K1, K2, phylloquinone, menaquinone

There is evidence that vitamin K contributes to normal blood clotting and to the maintenance of normal bones. 5 servings of MANA Powder or MANA Drink contains 75 mcg of vitamin K1 (phylloquinone) and 255 mcg of vitamin K2 (menaquinone type 7).

Enjoy MANA as part of your varied and balanced diet and healthy lifestyle. MANA is suitable for all healthy adults.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1228/epdf


Zinc

Zinc contributes to normal acid-base metabolism, to normal carbohydrate metabolism, to normal cognitive function and to normal DNA synthesis. Further, it contributes to normal fertility and reproduction, to normal macronutrient metabolism, to normal metabolism of fatty acids and to normal metabolism of vitamin A. It also contributes to normal protein synthesis, to the maintenance of normal bones, normal hair, normal nails and skin. Zinc contributes to the maintenance of normal testosterone levels in the blood, to the maintenance of normal vision, to the normal function of the immune system, to the protection of cells from oxidative stress and has a role in the process of cell division.

5 servings of MANA Powder or MANA Drink contains 10 mg of zinc.

Enjoy MANA as part of a varied and balanced diet and a healthy lifestyle. MANA is suitable for every healthy adult.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1819/epdf

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2014.3653/epdf


Iron

Iron contributes to normal cognitive function, to normal energy-yielding metabolism, to normal formation of red blood cells and haemoglobin and to normal oxygen transport in the body. Iron contributes to the normal function of the immune system, to the reduction of tiredness and fatigue and has a role in the process of cell division. 5 servings of powdered MANA or MANA Drink contains 15 mg of iron.

Enjoy MANA as part of a varied and balanced diet and a healthy lifestyle. MANA is suitable for every healthy adult.

Source of informations: EU Comission regulation 432/2012

Clinical studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2014.3515/epdf